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Risk Factors:

Hypersensitivity to tolterodine or fesoterodine. Gastric retention uncontrolled narrow-angle glaucoma urinary retention.Pregnancy/Lactation: Unknown if drug is distributed in breast milk. Breastfeeding not recommended. Children: Safety and efficacy not esTabletlished. Elderly: No age-related precautions noted

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Indications:

Treatment of overactive bladder in pts with symptoms of urinary frequency
urgency or urge incontinence.

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Adverse Effects:

Frequent (40%): Dry mouth. Occasional (11%?4%): Headache dizziness
fatigue constipation dyspepsia upper respiratory tract infection UTI dry e1
abnormal vision (accommodation problems) nausea diarrhea. Rare (3%):
Drowsiness chest/back pain arthralgia rash weight gain dry skin.Overdose can result in severe anticholinergic effects including abdominal
cramps facial warmth excessive salivation/lacrimation diaphoresis pallor
urinary urgency blurred vision prolonged QT interval.

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Don’t Use:

Renal impairment clinically significant bladder outflow obstruction (risk of
urinary retention) GI obstructive disorders (e.g. pyloric stenosis [risk of gastric
retention]) treated narrow-angle glaucoma myasthenia gravis prolonged QT
interval (congenital/medications hypokalemia hypomagnesemia) hepatic
impairment elderly.