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Risk Factors:

Pregnancy: Risk cannot be ruled out. Lactation: Caution advised or effect undetermined. Contraindications: Acute Ml

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Indications:

Depression with or without anxiety.

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Adverse Effects:

Drowsiness dizziness headache nausea postural hypotension. Priapism blood dyscrasias hepatic dysfunction(discontinue) hyponatraemia wt loss anorexia
SIADH CNS disturbances arrhythmias nasal congestion dyspnoea skin reactions flu like symptoms.

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Don’t Use:

Epilepsy severe hepatic renal or cardiovascular disease psychosis hyperthyroidism BPH narrow angle glaucoma. Monitor for suicidal ideation. Advise
patients to report signs of hepatic impairment incl asthenia anorexia GI upset jaundice. Elderly. Withdraw gradually.