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Risk Factors:

Contraindications: Hypersensitivity to cilostazol. HF of any severity.Pregnancy/Lactation: Unknown if drug crosses placenta or is distributed in breast milk. Children: Safety and efficacy not esTabletlished. Elderly: No agerelated precautions noted

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Indications:

Reduces symptoms of intermittent claudication (increases walking distance).

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Adverse Effects:

Frequent (34%?10%): Headache diarrhea palpitations dizziness pharyngitis.
Occasional (7%?3%): Nausea rhinitis back pain peripheral edema dyspepsia
abdominal pain tachycardia cough flatulence myalgia. Rare (2%?1%): Leg
cramps paresthesia rash vomiting.
Adverse effects/toxic reactions
Overdose noted as severe headache diarrhea hypotension cardiac arrhythmias.
May increase risk of endocardial hemorrhage fibrosis of left ventricle intimal
thickening of coronary artery

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Don’t Use:

Hemostatic disorders or active bleeding (bleeding peptic ulcer
intracranial bleeding). Severe underlying heart disease thrombocytopenia pts
receiving other platelet aggregation inhibitors moderate to severe hepatic
impairment severe renal impairment.