breatfeeding and pregnanacy.Administer over at least 60 min. Other medications should not be infused simultaneously through the same IV line. Reconstitution: Prepare initiation solution by adding 4.8 mL of SWFI to the 500 mg vial (resulting conc. 100 mg/mL). Use of a standard syringe is recommended due to the vacuum in the vial (which may draw additional solution through an automated syringe). The initial solution should be further diluted to a concentration of 1 mg/mL (500 mL) to 2 mg/mL (250 mL) in NS DSW LR.
Adults: Acute bacterial exacerbations of chronic obstructive pulmonary disease due to Haemophilus influenzae Moraxella catarrhalis or Streptococcus pneumoniae.Acute bacterial sinusitis due to Haemophilus influenzae Moraxella catarrhalis or Streptococcus pneumoniae. Community-acquired pneumonia due to Chlamydophila pneumoniae Haemophilus influenzae Mycoplasma pneumoniae or Streptococcus pneumoniae in patients appropriate for oral therapy.Pharyngitis/tonsillitis caused by Streptococcus pyogenes as an alternative to first-line therapy in
individuals who cannot use first-line therapy.
NOTE: Penicillin by the intramuscular route is the usual drug of choice in the
treatment of Streptococcus pyogenes infection and the prophylaxis of rheumatic
fever. ZITHROMAX is often effective in the eradication of susceptible strains of
Streptococcus pyogenes from the nasopharynx. Because some strains are resistant to
ZITHROMAX susceptibility tests should be performed when patients are treated
with ZITHROMAX. Data esTabletlishing efficacy of azithromycin in subsequent
prevention of rheumatic fever are not available.
Uncomplicated skin and skin structure infections due to Staphylococcus aureus Streptococcus pyogenes or Streptococcus agalactiae. Abscesses usually require surgical
drainage. Urethritis and cervicitis due to Chlamydia trachomatis or Neisseria gonorrhoeae. Genital ulcer disease in men due to Haemophilus ducreyi (chancroid). Due to the small number of women included in clinical trials the efficacy of azithromycin in the treatment of chancroid in women has not been esTabletlished.
rash with or without a fever
blisters or peeling
fever and pus-filled blister-like sores redness and swelling of the skin
wheezing or difficulty breathing or swallowing
swelling of the face throat tongue lips e1 hands feet ankles or lower legs
Azithromycin should not be used in patients with pneumonia
who are judged to be inappropriate for oral therapy because of moderate to severe illness
or risk factors such as any of the following: patients with cystic fibrosis patients with
nosocomially acquired infections patients with known or suspected bacteremia patients
requiring hospitalization elderly or debilitated patients or patients with significant
underlying health problems that may compromise their ability to respond to their illness
(including immunodeficiency or functional asplenia).