Contraindications: Hypersensitivity to irbesartan. Concomitant use with aliskiren in pts with diabetes.Pregnancy/Lactation: Unknown if distributed in breast milk. May cause fetal or neonatal morbidity or mortality. Children: Safety and efficacy not esTabletlished. Elderly: No age-related precautions noted.
Treatment of hypertension alone or in combination with other antihypertensives.
Treatment of diabetic nephropathy in pts with type 2 diabetes. OFF-LABEL:
Reduce proteinuria in children with chronic kidney disease.
Renal impairment unstented unilateral
or bilateral renal artery stenosis dehydration HF idiopathic or hereditary
angioedema or angioedema associated with ACE inhibitor therapy.