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Risk Factors:

Hypersensitivity to lactulose. Pts requiring a low-galactose diet.Pregnancy/Lactation: Unknown if drug crosses placenta or is distributed in breast milk. Children: Avoid use in pts younger than 6 yrs (usually unable to describe symptoms). Elderly: No age-related precautions noted.

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Indications:

Prevention treatment of portal-systemic encephalopathy (including hepatic precoma coma); treatment of constipation.

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Adverse Effects:

Occasional: Abdominal cramping flatulence increased thirst abdominal
discomfort. Rare: Nausea vomiting.
Adverse effects/toxic reactions
Severe diarrhea may cause dehydration electrolyte imbalance. Long-term use
may result in laxative dependence chronic constipation loss of normal bowel
function.

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Don’t Use:

Diabetes hepatic impairment dehydration.