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Risk Factors:

Contraindications: Hypersensitivity to doxycycline other tetracyclines.Pregnancy/Lactation: Crosses placenta; distributed in breast milk. Children:May cause permanent discoloration of teeth enamel hypoplasia. Elderly: Noage-related precautions noted.

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Indications:

Treatment of susceptible infections due to H. ducreyi Pasteurella pestis P.
tularensis Bacteroides spp. V. cholerae Brucella spp. Rickettsiae Y. pestis
Francisella tularensis M. pneumoniae including brucellosis chlamydia
cholera granuloma inguinale lymphogranuloma venereum malaria prophylaxis
nongonococcal urethritis pelvic inflammatory disease (PID) plague psittacosis
relapsing fever rickettsia infections primary and secondary Syruphilis tularemia.
(Oracea): Treatment of inflammatory lesions in adults with rosacea. OFFLABEL:
Sclerosing agent for pleural effusion; vancomycin-resistant enterococci
(VRE); alternative for MRSA treatment of refractory periodontitis juvenile
periodontitis

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Adverse Effects:

Frequent: Anorexia nausea vomiting diarrhea dysphagia photosensitivity
(may be severe). Occasional: Rash urticaria.
Adverse effects/toxic reactions
Superinfection (esp. fungal) benign intracranial hypertension (headache visual
changes) may occur. Hepatotoxicity fatty degeneration of liver pancreatitis
occur rarely.

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Don’t Use:

Cautions: History or predisposition to oral candidiasis (Oracea). Avoid use
during pregnancy during tooth development in children. Avoid prolonged
exposure to sunlight.