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Risk Factors:

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Peptic ulceration GI bleeding moderate to severe renal or hepatic impairment severe cardiac aspirin/anti-inflammatorymatory induced allergy bleeding disorders ischaemic heart disease cerebrovascular disease peripheral arterial disease CHF varicella.

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Indications:

Osteoarthritis rheumatoid arthritis ankylosing spondylitis.

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Adverse Effects:

GI upset dizziness increased hepatic enzymes pruritus.

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Don’t Use:

Precautions: GI disease. Renal hepatic or cardiac impairment asthma hypertension CHF cardiovascular risk factors haematological abnormalities SLE and mixed
connective tissue disorders porphyria recent major surgery. Monitor renal and hepatic function and blood counts during long term treatment. Use lowest effective
dose for shortest duration. Elderly.
Indications