Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Juvenile diabetes with ketosis impairment of renal function stress diabetic coma severe trauma infections surgery impaired adrenocortical function Porphyria.
Nausea and sensation of fullness are exceptional. Change in haematopoietic system are rare. Hypoglycaemia GI upset skin reactions. Rarely hepatic function
abnormalities hepatic failure hepatitis jaundice blood dyscrasias transient visual disturbances.
Precautions: Cross-sensitivity to sulfonamides and sulfonamide derivative. Mild to moderate renal or hepatic impairment obesity GP6D deficiency. Elderly.