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Risk Factors:

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Active peptic ulcer GI bleeding aspirin/anti-inflammatorymatory induced allergy severe hepatic or renal failure severe CHF active inflammatory bowel disease cerebrovascular bleeding bleeding disorders. Treatment of pain after CABG.

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Don’t Use:

Precautions: Congestive heart failure liver cirrhosis nephrotic syndrome renal failure hypovolaemia GI upset hypertension ischaemic heart disease peripheral
arterial disease cerebrovascular disease other cardiovascular risk factors. Elderly.