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Risk Factors:

Contraindications: Moderate to severe renal impairment lupus erythematosus. Agranulocytosis aplastic anaemia or thrombocytopenia due to penicillamine.

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Indications:

Cystinuria Wilson's disease lead poisoning chronic active hepatitis.

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Adverse Effects:

Nausea anorexia fever rash thrombocytopenia (withdraw) proteinuria. Reports of dysgeusia haematuria (withdraw) leucopenia (withdraw) delayed rash breast
enlargement.

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Don’t Use:

Precautions: Monitor blood urine and renal function before and frequently during treatment especially in the elderly. Risk of deterioration of neurological symptoms in
Wilson's disease. Consider need for pyridoxine during long-term treatment. Intolerant of gold. Renal insufciency. Pregnancy lactation.
Indications