Emetil 5 mg
Advise to Patient:
Contraindications: Hypersensitivity to prochlorperazine. Coma or presence of large amounts of CNS depressants (e.g. alcohol opioids). Use in children younger than 2 yrs or weighing less than 9 kg. Postoperative nausea/vomiting following pediatric surgery..Pregnancy/Lactation: Crosses placenta. Distributed in breast milk. Children: Safety and efficacy not esTabletlished in pts weighing less than 9 kg or younger than 2 yrs. Elderly: More susceptible to orthostatic hypotension anticholinergic effects (e.g. dry mouth) sedation extrapyramidal symptoms (EPS); lower dosage recommended.
Management of severe nausea/vomiting. Treatment of acute or chronic
psychosis nonpsychotic anxiety. OFF-LABEL: Behavioral syndromes in
dementia psychosis/agitation related to Alzheimer?s dementia.
Frequent: Drowsiness hypotension dizziness fainting (commonly occurring
after first dose occasionally after subsequent doses rarely with oral form).
Occasional: Dry mouth blurred vision lethargy constipation diarrhea
myalgia nasal congestion peripheral edema urinary retention.
Adverse effects/toxic reactions
Extrapyramidal symptoms (EPS) appear dose related and are divided into three
categories: akathisia (e.g. inability to sit still tapping of feet) parkinsonian
symptoms (mask-like face tremors shuffling gait hypersalivation) acute
dystonias (torticollis [neck muscle spasm] opisthotonos [rigidity of back
muscles] oculogyric crisis [rolling back of e1]). Dystonic reaction may
produce diaphoresis pallor. Tardive dyskinesia (tongue protrusion puffing of
cheeks puckering of mouth) occurs rarely and may be irreversible. Abrupt
withdrawal after long-term therapy may precipitate nausea vomiting gastritis
dizziness tremors. Blood dyscrasias particularly agranulocytosis mild
leukopenia may occur. May lower seizure threshold
History of seizures Parkinson?s disease
elderly pts at risk for pneumonia severe renal/hepatic impairment decreased GI
motility urinary retention visual problems narrow-angle glaucoma paralytic
ileus myasthenia gravis cerebrovascular/cardiovascular disease.