Emetil 5 mg
Advise to Patient:
oral
Risk Factors:
Contraindications: Hypersensitivity to prochlorperazine. Coma or presence of large amounts of CNS depressants (e.g. alcohol opioids). Use in children younger than 2 yrs or weighing less than 9 kg. Postoperative nausea/vomiting following pediatric surgery..Pregnancy/Lactation: Crosses placenta. Distributed in breast milk. Children: Safety and efficacy not esTabletlished in pts weighing less than 9 kg or younger than 2 yrs. Elderly: More susceptible to orthostatic hypotension anticholinergic effects (e.g. dry mouth) sedation extrapyramidal symptoms (EPS); lower dosage recommended.
Indications:
Management of severe nausea/vomiting. Treatment of acute or chronic
psychosis nonpsychotic anxiety. OFF-LABEL: Behavioral syndromes in
dementia psychosis/agitation related to Alzheimer?s dementia.
Adverse Effects:
Frequent: Drowsiness hypotension dizziness fainting (commonly occurring
after first dose occasionally after subsequent doses rarely with oral form).
Occasional: Dry mouth blurred vision lethargy constipation diarrhea
myalgia nasal congestion peripheral edema urinary retention.
Adverse effects/toxic reactions
Extrapyramidal symptoms (EPS) appear dose related and are divided into three
categories: akathisia (e.g. inability to sit still tapping of feet) parkinsonian
symptoms (mask-like face tremors shuffling gait hypersalivation) acute
dystonias (torticollis [neck muscle spasm] opisthotonos [rigidity of back
muscles] oculogyric crisis [rolling back of e1]). Dystonic reaction may
produce diaphoresis pallor. Tardive dyskinesia (tongue protrusion puffing of
cheeks puckering of mouth) occurs rarely and may be irreversible. Abrupt
withdrawal after long-term therapy may precipitate nausea vomiting gastritis
dizziness tremors. Blood dyscrasias particularly agranulocytosis mild
leukopenia may occur. May lower seizure threshold
Don’t Use:
History of seizures Parkinson?s disease
elderly pts at risk for pneumonia severe renal/hepatic impairment decreased GI
motility urinary retention visual problems narrow-angle glaucoma paralytic
ileus myasthenia gravis cerebrovascular/cardiovascular disease.